Progress of thrombus formation and research on the structure-activity relationship for antithrombotic drugsReview article Published on 2022-01-012022-10-05 Journal: European journal of medicinal chemistry [Category] 비임상, [키워드] activity Anticoagulants Antithrombotic Antithrombotic drugs approved drug AstraZeneca bleeding blood clot candidate Cardio-cerebrovascular diseases category cause Compound COVID disease drug effective effort Factor Health high risk inhibitor mechanism Myocardial infarction onset of action Platelet Population Prevalence Progress promote receiving reported Research stroke therapeutic window thromboembolic disease thrombosis thrombotic disorder thrombotic disorders Thrombus thrombus formation unstable angina Vaccine [DOI] 10.1016/j.ejmech.2021.114035 [Article Type] Review article
Bioactive Molecules Derived from Snake Venoms with Therapeutic Potential for the Treatment of Thrombo-Cardiovascular Disorders Associated with COVID-19COVID-19와 관련된 혈전-심혈관 질환 치료를 위한 치료 가능성을 지닌 뱀 독에서 추출한 생리활성 분자Review Published on 2021-12-012022-09-11 Journal: The protein journal [Category] SARS, 변종, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome Algae Anti-inflammatory Anticoagulant antimicrobial antiplatelet Antiplatelet peptides Antithrombotic Antithrombotic compounds Antiviral antiviral proteins antiviral strategy Bioactivity Biotherapeutics Coagulopathy Compound compounds coronavirus coronavirus disease COVID-19 cytokine Cytokine storm effective Endothelial dysfunction expected genetic difference genetic differences IMPROVE induce Infection Inflammatory responses management mechanism molecule Nature offer pandemic peptide peptides plant platelet hyperactivation Potential Protein respiratory response SARS-CoV-2 SARS-CoV-2 variants Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 Sickness snake Snake venom Snake Venoms Snake venoms. therapeutic Therapeutics thrombosis thrombotic disorder thrombotic disorders variant variants Venom Viral viral respiratory with COVID-19 [DOI] 10.1007/s10930-021-10019-4 PMC 바로가기 [Article Type] Review
D-dimer as a biomarker for assessment of COVID-19 prognosis: D-dimer levels on admission and its role in predicting disease outcome in hospitalized patients with COVID-19COVID-19 예후 평가를위한 바이오 마커로서의 D-Dimer : COVID-19를 가진 입원 환자에서 입원 및 질병 결과를 예측하는 데있어서 D-Dimer 수준.Research Article Published on 2021-08-262022-08-13 Journal: PLoS ONE [Category] Biochemistry, MERS, SARS, 바이오마커, [키워드] 95% CI Accuracy adjusted Admission age an area analyzed Biomarker calculate characteristic clinical confirmed COVID-19 case coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 patients Cox proportional hazard Cox proportional hazards regression analysis Cutoff cutoff value D-dimer D-dimer level D-dimer value determine died dimer disease Elevation fibrinogen Fibrinogen Equivalent Unit hazard ratio hospital Hospital mortality Hospital stay hospitalized patient hospitals in Kathmandu immunofluorescence assay laboratory parameter Laboratory parameters Mortality on admission outcome Patient patients with COVID-19 poor prognosis predict Predictive Predictive value Prognosis receiver operating characteristic receiver operating characteristic curve recorded regression analysis reported respiratory Respiratory illness Result ROC Curve sensitivity specificity surviving patient surviving patients thrombotic disorders two group two groups was measured was used with COVID-19 [DOI] 10.1371/journal.pone.0256744 PMC 바로가기 [Article Type] Research Article